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    "pmid": "40701556",
    "doi": "10.14309/ajg.0000000000003463",
    "pmc": null,
    "title": "ACG Clinical Guideline Update: Ulcerative Colitis in Adults",
    "authors": [
      "Rubin DT",
      "Ananthakrishnan AN",
      "Siegel CA",
      "Barnes EL",
      "Long MD"
    ],
    "journal": "The American journal of gastroenterology",
    "year": 2025,
    "type": "Clinical guideline",
    "evidence": 5,
    "topics": [
      "ibd-diagnosis"
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  {
    "pmid": "40701562",
    "doi": "10.14309/ajg.0000000000003465",
    "pmc": null,
    "title": "ACG Clinical Guideline: Management of Crohn's Disease in Adults",
    "authors": [
      "Lichtenstein GR",
      "Loftus EV",
      "Afzali A",
      "Long MD",
      "Barnes EL",
      "Isaacs KL",
      "Ha CY"
    ],
    "journal": "The American journal of gastroenterology",
    "year": 2025,
    "type": "Clinical guideline",
    "evidence": 5,
    "topics": [
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  {
    "pmid": "40528309",
    "doi": "10.1002/jpn3.70096",
    "pmc": null,
    "title": "Management of paediatric ulcerative colitis, part 2: Acute severe colitis-An updated evidence-based consensus guideline from the European Society of Paediatric Gastroenterology, Hepatology and Nutrition and the European Crohn's and Colitis Organization",
    "authors": [
      "Assa A",
      "Aloi M",
      "Van Biervliet S",
      "Bronsky J",
      "di Carpi JM",
      "Gasparetto M",
      "Gianolio L",
      "Gordon H",
      "Hojsak I",
      "Hudson AS",
      "Hussey S",
      "Van Limbergen J",
      "Miele E",
      "Norsa L",
      "Olén O",
      "Pellino G",
      "van Rheenen P",
      "de Ridder L",
      "Russell RK",
      "Shouval DS",
      "Trindade E",
      "Dan T",
      "Wilson DC",
      "Yerushalmy-Feler A",
      "Wine E"
    ],
    "journal": "Journal of pediatric gastroenterology and nutrition",
    "year": 2025,
    "type": "Clinical guideline",
    "evidence": 5,
    "topics": [
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      "ibd-epidemiology"
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  {
    "pmid": "40677018",
    "doi": "10.1002/jpn3.70097",
    "pmc": "PMC12408984",
    "title": "Management of paediatric ulcerative colitis, part 1: Ambulatory care-An updated evidence-based consensus guideline from the European Society of Paediatric Gastroenterology, Hepatology and Nutrition and the European Crohn's and Colitis Organisation",
    "authors": [
      "Wine E",
      "Aloi M",
      "Van Biervliet S",
      "Bronsky J",
      "di Carpi JM",
      "Gasparetto M",
      "Gianolio L",
      "Gordon H",
      "Hojsak I",
      "Hudson AS",
      "Hussey S",
      "van Limbergen J",
      "Miele E",
      "Norsa L",
      "Olén O",
      "Pellino G",
      "van Rheenen P",
      "de Ridder L",
      "Russell RK",
      "Shouval DS",
      "Trindade E",
      "Turner D",
      "Wilson DC",
      "Yerushalmy Feler A",
      "Assa A"
    ],
    "journal": "Journal of pediatric gastroenterology and nutrition",
    "year": 2025,
    "type": "Clinical guideline",
    "evidence": 5,
    "topics": [
      "ibd-diagnosis",
      "ibd-epidemiology"
    ]
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  {
    "pmid": "39056556",
    "doi": "10.14309/ajg.0000000000002973",
    "pmc": null,
    "title": "Using Diet to Treat Inflammatory Bowel Disease: A Systematic Review",
    "authors": [
      "Gleave A",
      "Shah A",
      "Tahir U",
      "Blom JJ",
      "Dong E",
      "Patel A",
      "Marshall JK",
      "Narula N"
    ],
    "journal": "The American journal of gastroenterology",
    "year": 2025,
    "type": "Systematic review",
    "evidence": 5,
    "topics": [
      "ibd-diet",
      "ibd-trigger-foods"
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  {
    "pmid": "39572132",
    "doi": "10.1053/j.gastro.2024.10.001",
    "pmc": "PMC12162142",
    "title": "AGA Living Clinical Practice Guideline on Pharmacological Management of Moderate-to-Severe Ulcerative Colitis",
    "authors": [
      "Singh S",
      "Loftus EV Jr",
      "Limketkai BN",
      "Haydek JP",
      "Agrawal M",
      "Scott FI",
      "Ananthakrishnan AN"
    ],
    "journal": "Gastroenterology",
    "year": 2024,
    "type": "Clinical guideline",
    "evidence": 5,
    "topics": [
      "ibd-diagnosis"
    ]
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  {
    "pmid": "38878002",
    "doi": "10.1093/ecco-jcc/jjae089",
    "pmc": null,
    "title": "ECCO Guidelines on Therapeutics in Crohn's Disease: Surgical Treatment",
    "authors": [
      "Adamina M",
      "Minozzi S",
      "Warusavitarne J",
      "Buskens CJ",
      "Chaparro M",
      "Verstockt B",
      "Kopylov U",
      "Yanai H",
      "Vavricka SR",
      "Sigall-Boneh R",
      "Sica GS",
      "Reenaers C",
      "Peros G",
      "Papamichael K",
      "Noor N",
      "Moran GW",
      "Maaser C",
      "Luglio G",
      "Kotze PG",
      "Kobayashi T",
      "Karmiris K",
      "Kapizioni C",
      "Iqbal N",
      "Iacucci M",
      "Holubar S",
      "Hanzel J",
      "Sabino JG",
      "Gisbert JP",
      "Fiorino G",
      "Fidalgo C",
      "Ellu P",
      "El-Hussuna A",
      "de Groof J",
      "Czuber-Dochan W",
      "Casanova MJ",
      "Burisch J",
      "Brown SR",
      "Bislenghi G",
      "Bettenworth D",
      "Battat R",
      "Atreya R",
      "Allocca M",
      "Agrawal M",
      "Raine T",
      "Gordon H",
      "Myrelid P"
    ],
    "journal": "Journal of Crohn's & colitis",
    "year": 2024,
    "type": "Clinical guideline",
    "evidence": 5,
    "topics": [
      "ibd-diagnosis"
    ]
  },
  {
    "pmid": "38276922",
    "doi": "10.1053/j.gastro.2023.11.303",
    "pmc": null,
    "title": "AGA Clinical Practice Update on Diet and Nutritional Therapies in Patients With Inflammatory Bowel Disease: Expert Review",
    "authors": [
      "Hashash JG",
      "Elkins J",
      "Lewis JD",
      "Binion DG"
    ],
    "journal": "Gastroenterology",
    "year": 2024,
    "type": "Clinical guideline",
    "evidence": 5,
    "topics": [
      "ibd-diagnosis",
      "ibd-trigger-foods"
    ]
  },
  {
    "pmid": "39425738",
    "doi": "10.1053/j.gastro.2024.07.046",
    "pmc": "PMC12148344",
    "title": "Comparative Efficacy of Advanced Therapies for Management of Moderate-to-Severe Ulcerative Colitis: 2024 American Gastroenterological Association Evidence Synthesis",
    "authors": [
      "Ananthakrishnan AN",
      "Murad MH",
      "Scott FI",
      "Agrawal M",
      "Haydek JP",
      "Limketkai BN",
      "Loftus EV Jr",
      "Singh S"
    ],
    "journal": "Gastroenterology",
    "year": 2024,
    "type": "Meta-analysis",
    "evidence": 5,
    "topics": [
      "ibd-biologics"
    ]
  },
  {
    "pmid": "38834296",
    "doi": "10.1136/gutjnl-2024-332489",
    "pmc": "PMC11610420",
    "title": "Acute severe ulcerative colitis trials: the past, the present and the future",
    "authors": [
      "Honap S",
      "Jairath V",
      "Sands BE",
      "Dulai PS",
      "Danese S",
      "Peyrin-Biroulet L"
    ],
    "journal": "Gut",
    "year": 2024,
    "type": "Systematic review",
    "evidence": 5,
    "topics": [
      "ibd-epidemiology"
    ]
  },
  {
    "pmid": "39686992",
    "doi": "10.7717/peerj.18692",
    "pmc": "PMC11648686",
    "title": "Efficacy of different dietary therapy strategies in active pediatric Crohn's disease: a systematic review and network meta-analysis",
    "authors": [
      "Ma J",
      "Chong J",
      "Qiu Z",
      "Wang Y",
      "Chen T",
      "Chen Y"
    ],
    "journal": "PeerJ",
    "year": 2024,
    "type": "Meta-analysis",
    "evidence": 5,
    "topics": [
      "ibd-trigger-foods"
    ]
  },
  {
    "pmid": "38236326",
    "doi": "10.1007/s15010-023-02156-y",
    "pmc": "PMC11142967",
    "title": "Risk factors for herpes zoster infections: a systematic review and meta-analysis unveiling common trends and heterogeneity patterns",
    "authors": [
      "Steinmann M",
      "Lampe D",
      "Grosser J",
      "Schmidt J",
      "Hohoff ML",
      "Fischer A",
      "Greiner W"
    ],
    "journal": "Infection",
    "year": 2024,
    "type": "Meta-analysis",
    "evidence": 5,
    "topics": [
      "ibd-quality-of-life"
    ]
  },
  {
    "pmid": "37513532",
    "doi": "10.3390/nu15143114",
    "pmc": "PMC10384554",
    "title": "High-Fiber Diet and Crohn's Disease: Systematic Review and Meta-Analysis",
    "authors": [
      "Serrano Fernandez V",
      "Seldas Palomino M",
      "Laredo-Aguilera JA",
      "Pozuelo-Carrascosa DP",
      "Carmona-Torres JM"
    ],
    "journal": "Nutrients",
    "year": 2023,
    "type": "Meta-analysis",
    "evidence": 5,
    "topics": [
      "ibd-diet"
    ]
  },
  {
    "pmid": "37836478",
    "doi": "10.3390/nu15194194",
    "pmc": "PMC10574654",
    "title": "Dietary Interventions in Ulcerative Colitis: A Systematic Review of the Evidence with Meta-Analysis",
    "authors": [
      "Herrador-López M",
      "Martín-Masot R",
      "Navas-López VM"
    ],
    "journal": "Nutrients",
    "year": 2023,
    "type": "Meta-analysis",
    "evidence": 5,
    "topics": [
      "ibd-diet",
      "ibd-trigger-foods"
    ]
  },
  {
    "pmid": "38177426",
    "doi": "10.1038/s43588-023-00464-9",
    "pmc": null,
    "title": "Single-cell meta-analysis of inflammatory bowel disease with scIBD",
    "authors": [
      "Nie H",
      "Lin P",
      "Zhang Y",
      "Wan Y",
      "Li J",
      "Yin C",
      "Zhang L"
    ],
    "journal": "Nature computational science",
    "year": 2023,
    "type": "Meta-analysis",
    "evidence": 5,
    "topics": [
      "ibd-biologics"
    ]
  },
  {
    "pmid": "35863682",
    "doi": "10.1016/j.cgh.2022.06.030",
    "pmc": null,
    "title": "Global Hospitalization Trends for Crohn's Disease and Ulcerative Colitis in the 21st Century: A Systematic Review With Temporal Analyses",
    "authors": [
      "Buie MJ",
      "Quan J",
      "Windsor JW",
      "Coward S",
      "Hansen TM",
      "King JA",
      "Kotze PG",
      "Gearry RB",
      "Ng SC",
      "Mak JWY",
      "Abreu MT",
      "Rubin DT",
      "Bernstein CN",
      "Banerjee R",
      "Yamamoto-Furusho JK",
      "Panaccione R",
      "Seow CH",
      "Ma C",
      "Underwood FE",
      "Ahuja V",
      "Panaccione N",
      "Shaheen AA",
      "Holroyd-Leduc J",
      "Kaplan GG",
      "Balderramo D",
      "Chong VH",
      "Juliao-Baños F",
      "Dutta U",
      "Simadibrata M",
      "Kaibullayeva J",
      "Sun Y",
      "Hilmi I",
      "Raja Ali RA",
      "Paudel MS",
      "Altuwaijri M",
      "Hartono JL",
      "Wei SC",
      "Limsrivilai J",
      "El Ouali S",
      "Vergara BI",
      "Dao VH",
      "Kelly P",
      "Hodges P",
      "Miao Y",
      "Li M"
    ],
    "journal": "Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association",
    "year": 2023,
    "type": "Meta-analysis",
    "evidence": 5,
    "topics": [
      "ibd-epidemiology"
    ]
  },
  {
    "pmid": "37686856",
    "doi": "10.3390/nu15173824",
    "pmc": "PMC10489664",
    "title": "Nutrition, Nutritional Status, Micronutrients Deficiency, and Disease Course of Inflammatory Bowel Disease",
    "authors": [
      "Valvano M",
      "Capannolo A",
      "Cesaro N",
      "Stefanelli G",
      "Fabiani S",
      "Frassino S",
      "Monaco S",
      "Magistroni M",
      "Viscido A",
      "Latella G"
    ],
    "journal": "Nutrients",
    "year": 2023,
    "type": "Systematic review",
    "evidence": 5,
    "topics": [
      "ibd-quality-of-life"
    ]
  },
  {
    "pmid": "34856198",
    "doi": "10.1016/S2468-1253(21)00377-0",
    "pmc": null,
    "title": "Efficacy and safety of biologics and small molecule drugs for patients with moderate-to-severe ulcerative colitis: a systematic review and network meta-analysis",
    "authors": [
      "Lasa JS",
      "Olivera PA",
      "Danese S",
      "Peyrin-Biroulet L"
    ],
    "journal": "The lancet. Gastroenterology & hepatology",
    "year": 2022,
    "type": "Meta-analysis",
    "evidence": 5,
    "topics": [
      "ibd-biologics"
    ]
  },
  {
    "pmid": "33798711",
    "doi": "10.1016/j.cgh.2021.03.034",
    "pmc": null,
    "title": "Dual Biologic or Small Molecule Therapy for Treatment of Inflammatory Bowel Disease: A Systematic Review and Meta-analysis",
    "authors": [
      "Ahmed W",
      "Galati J",
      "Kumar A",
      "Christos PJ",
      "Longman R",
      "Lukin DJ",
      "Scherl E",
      "Battat R"
    ],
    "journal": "Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association",
    "year": 2022,
    "type": "Meta-analysis",
    "evidence": 5,
    "topics": [
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  {
    "pmid": "35676620",
    "doi": "10.1186/s12876-022-02347-1",
    "pmc": "PMC9178865",
    "title": "Comparative efficacy and safety of infliximab and vedolizumab therapy in patients with inflammatory bowel disease: a systematic review and meta-analysis",
    "authors": [
      "Peyrin-Biroulet L",
      "Arkkila P",
      "Armuzzi A",
      "Danese S",
      "Guardiola J",
      "Jahnsen J",
      "Lees C",
      "Louis E",
      "Lukáš M",
      "Reinisch W",
      "Roblin X",
      "Jang M",
      "Byun HG",
      "Kim DH",
      "Lee SJ",
      "Atreya R"
    ],
    "journal": "BMC gastroenterology",
    "year": 2022,
    "type": "Meta-analysis",
    "evidence": 5,
    "topics": [
      "ibd-biologics"
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  {
    "pmid": "34757139",
    "doi": "10.1053/j.gastro.2021.10.037",
    "pmc": null,
    "title": "Efficacy of Biologic Drugs in Short-Duration Versus Long-Duration Inflammatory Bowel Disease: A Systematic Review and an Individual-Patient Data Meta-Analysis of Randomized Controlled Trials",
    "authors": [
      "Ben-Horin S",
      "Novack L",
      "Mao R",
      "Guo J",
      "Zhao Y",
      "Sergienko R",
      "Zhang J",
      "Kobayashi T",
      "Hibi T",
      "Chowers Y",
      "Peyrin-Biroulet L",
      "Colombel JF",
      "Kaplan GG",
      "Chen MH"
    ],
    "journal": "Gastroenterology",
    "year": 2022,
    "type": "Meta-analysis",
    "evidence": 5,
    "topics": [
      "ibd-biologics"
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  {
    "pmid": "34995526",
    "doi": "10.1053/j.gastro.2021.12.282",
    "pmc": null,
    "title": "Twenty-first Century Trends in the Global Epidemiology of Pediatric-Onset Inflammatory Bowel Disease: Systematic Review",
    "authors": [
      "Kuenzig ME",
      "Fung SG",
      "Marderfeld L",
      "Mak JWY",
      "Kaplan GG",
      "Ng SC",
      "Wilson DC",
      "Cameron F",
      "Henderson P",
      "Kotze PG",
      "Bhatti J",
      "Fang V",
      "Gerber S",
      "Guay E",
      "Kotteduwa Jayawarden S",
      "Kadota L",
      "Maldonado D F",
      "Osei JA",
      "Sandarage R",
      "Stanton A",
      "Wan M",
      "Benchimol EI"
    ],
    "journal": "Gastroenterology",
    "year": 2022,
    "type": "Systematic review",
    "evidence": 5,
    "topics": [
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  {
    "pmid": "34844288",
    "doi": "10.1002/14651858.CD013531.pub2",
    "pmc": "PMC8629648",
    "title": "Interventions for the management of abdominal pain in Crohn's disease and inflammatory bowel disease",
    "authors": [
      "Sinopoulou V",
      "Gordon M",
      "Akobeng AK",
      "Gasparetto M",
      "Sammaan M",
      "Vasiliou J",
      "Dovey TM"
    ],
    "journal": "The Cochrane database of systematic reviews",
    "year": 2021,
    "type": "Systematic review",
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    "topics": [
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  {
    "pmid": "33811041",
    "doi": "10.1136/gutjnl-2020-322670",
    "pmc": "PMC8223641",
    "title": "Long-term dietary patterns are associated with pro-inflammatory and anti-inflammatory features of the gut microbiome",
    "authors": [
      "Bolte LA",
      "Vich Vila A",
      "Imhann F",
      "Collij V",
      "Gacesa R",
      "Peters V",
      "Wijmenga C",
      "Kurilshikov A",
      "Campmans-Kuijpers MJE",
      "Fu J",
      "Dijkstra G",
      "Zhernakova A",
      "Weersma RK"
    ],
    "journal": "Gut",
    "year": 2021,
    "type": "Meta-analysis",
    "evidence": 5,
    "topics": [
      "ibd-biologics"
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  {
    "pmid": "33359090",
    "doi": "10.1053/j.gastro.2020.12.031",
    "pmc": null,
    "title": "STRIDE-II: An Update on the Selecting Therapeutic Targets in Inflammatory Bowel Disease (STRIDE) Initiative of the International Organization for the Study of IBD (IOIBD): Determining Therapeutic Goals for Treat-to-Target strategies in IBD",
    "authors": [
      "Turner D",
      "Ricciuto A",
      "Lewis A",
      "D'Amico F",
      "Dhaliwal J",
      "Griffiths AM",
      "Bettenworth D",
      "Sandborn WJ",
      "Sands BE",
      "Reinisch W",
      "Schölmerich J",
      "Bemelman W",
      "Danese S",
      "Mary JY",
      "Rubin D",
      "Colombel JF",
      "Peyrin-Biroulet L",
      "Dotan I",
      "Abreu MT",
      "Dignass A"
    ],
    "journal": "Gastroenterology",
    "year": 2021,
    "type": "Systematic review",
    "evidence": 5,
    "topics": [
      "ibd-quality-of-life"
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  {
    "pmid": "33315591",
    "doi": "10.14309/ajg.0000000000001036",
    "pmc": null,
    "title": "ACG Clinical Guideline: Management of Irritable Bowel Syndrome",
    "authors": [
      "Lacy BE",
      "Pimentel M",
      "Brenner DM",
      "Chey WD",
      "Keefer LA",
      "Long MD",
      "Moshiree B"
    ],
    "journal": "The American journal of gastroenterology",
    "year": 2021,
    "type": "Clinical guideline",
    "evidence": 5,
    "topics": [
      "ibd-quality-of-life"
    ]
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  {
    "pmid": "33721557",
    "doi": "10.1016/S2468-1253(21)00014-5",
    "pmc": null,
    "title": "Prevalence of symptoms of anxiety and depression in patients with inflammatory bowel disease: a systematic review and meta-analysis",
    "authors": [
      "Barberio B",
      "Zamani M",
      "Black CJ",
      "Savarino EV",
      "Ford AC"
    ],
    "journal": "The lancet. Gastroenterology & hepatology",
    "year": 2021,
    "type": "Meta-analysis",
    "evidence": 5,
    "topics": [
      "ibd-quality-of-life"
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  },
  {
    "pmid": "33148393",
    "doi": "10.3238/arztebl.2020.0564",
    "pmc": "PMC8171548",
    "title": "Ulcerative Colitis-Diagnostic and Therapeutic Algorithms",
    "authors": [
      "Kucharzik T",
      "Koletzko S",
      "Kannengiesser K",
      "Dignass A"
    ],
    "journal": "Deutsches Arzteblatt international",
    "year": 2020,
    "type": "Meta-analysis",
    "evidence": 5,
    "topics": [
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  {
    "pmid": "30840605",
    "doi": "10.14309/ajg.0000000000000152",
    "pmc": null,
    "title": "ACG Clinical Guideline: Ulcerative Colitis in Adults",
    "authors": [
      "Rubin DT",
      "Ananthakrishnan AN",
      "Siegel CA",
      "Sauer BG",
      "Long MD"
    ],
    "journal": "The American journal of gastroenterology",
    "year": 2019,
    "type": "Clinical guideline",
    "evidence": 5,
    "topics": [
      "ibd-diagnosis"
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  },
  {
    "pmid": "31014995",
    "doi": "10.1053/j.gastro.2019.04.016",
    "pmc": null,
    "title": "Environmental Risk Factors for Inflammatory Bowel Diseases: An Umbrella Review of Meta-analyses",
    "authors": [
      "Piovani D",
      "Danese S",
      "Peyrin-Biroulet L",
      "Nikolopoulos GK",
      "Lytras T",
      "Bonovas S"
    ],
    "journal": "Gastroenterology",
    "year": 2019,
    "type": "Meta-analysis",
    "evidence": 5,
    "topics": [
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    ]
  },
  {
    "pmid": "29610508",
    "doi": "10.1038/ajg.2018.27",
    "pmc": null,
    "title": "ACG Clinical Guideline: Management of Crohn's Disease in Adults",
    "authors": [
      "Lichtenstein GR",
      "Loftus EV",
      "Isaacs KL",
      "Regueiro MD",
      "Gerson LB",
      "Sands BE"
    ],
    "journal": "The American journal of gastroenterology",
    "year": 2018,
    "type": "Clinical guideline",
    "evidence": 5,
    "topics": [
      "ibd-diagnosis"
    ]
  },
  {
    "pmid": "30044357",
    "doi": "10.1097/MPG.0000000000002035",
    "pmc": null,
    "title": "Management of Paediatric Ulcerative Colitis, Part 1: Ambulatory Care-An Evidence-based Guideline From European Crohn's and Colitis Organization and European Society of Paediatric Gastroenterology, Hepatology and Nutrition",
    "authors": [
      "Turner D",
      "Ruemmele FM",
      "Orlanski-Meyer E",
      "Griffiths AM",
      "de Carpi JM",
      "Bronsky J",
      "Veres G",
      "Aloi M",
      "Strisciuglio C",
      "Braegger CP",
      "Assa A",
      "Romano C",
      "Hussey S",
      "Stanton M",
      "Pakarinen M",
      "de Ridder L",
      "Katsanos K",
      "Croft N",
      "Navas-López V",
      "Wilson DC",
      "Lawrence S",
      "Russell RK"
    ],
    "journal": "Journal of pediatric gastroenterology and nutrition",
    "year": 2018,
    "type": "Clinical guideline",
    "evidence": 5,
    "topics": [
      "ibd-diagnosis"
    ]
  },
  {
    "pmid": "28131521",
    "doi": "10.1016/j.clnu.2016.12.027",
    "pmc": null,
    "title": "ESPEN guideline: Clinical nutrition in inflammatory bowel disease",
    "authors": [
      "Forbes A",
      "Escher J",
      "Hébuterne X",
      "Kłęk S",
      "Krznaric Z",
      "Schneider S",
      "Shamir R",
      "Stardelova K",
      "Wierdsma N",
      "Wiskin AE",
      "Bischoff SC"
    ],
    "journal": "Clinical nutrition (Edinburgh, Scotland)",
    "year": 2017,
    "type": "Systematic review",
    "evidence": 5,
    "topics": [
      "ibd-diet"
    ]
  },
  {
    "pmid": "28067908",
    "doi": "10.1038/ng.3760",
    "pmc": "PMC5289481",
    "title": "Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease",
    "authors": [
      "de Lange KM",
      "Moutsianas L",
      "Lee JC",
      "Lamb CA",
      "Luo Y",
      "Kennedy NA",
      "Jostins L",
      "Rice DL",
      "Gutierrez-Achury J",
      "Ji SG",
      "Heap G",
      "Nimmo ER",
      "Edwards C",
      "Henderson P",
      "Mowat C",
      "Sanderson J",
      "Satsangi J",
      "Simmons A",
      "Wilson DC",
      "Tremelling M",
      "Hart A",
      "Mathew CG",
      "Newman WG",
      "Parkes M",
      "Lees CW",
      "Uhlig H",
      "Hawkey C",
      "Prescott NJ",
      "Ahmad T",
      "Mansfield JC",
      "Anderson CA",
      "Barrett JC"
    ],
    "journal": "Nature genetics",
    "year": 2017,
    "type": "Meta-analysis",
    "evidence": 5,
    "topics": [
      "ibd-biologics"
    ]
  },
  {
    "pmid": "29050646",
    "doi": "10.1016/S0140-6736(17)32448-0",
    "pmc": null,
    "title": "Worldwide incidence and prevalence of inflammatory bowel disease in the 21st century: a systematic review of population-based studies",
    "authors": [
      "Ng SC",
      "Shi HY",
      "Hamidi N",
      "Underwood FE",
      "Tang W",
      "Benchimol EI",
      "Panaccione R",
      "Ghosh S",
      "Wu JCY",
      "Chan FKL",
      "Sung JJY",
      "Kaplan GG"
    ],
    "journal": "Lancet (London, England)",
    "year": 2017,
    "type": "Systematic review",
    "evidence": 5,
    "topics": [
      "ibd-epidemiology"
    ]
  },
  {
    "pmid": "26192919",
    "doi": "10.1038/ng.3359",
    "pmc": "PMC4881818",
    "title": "Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations",
    "authors": [
      "Liu JZ",
      "van Sommeren S",
      "Huang H",
      "Ng SC",
      "Alberts R",
      "Takahashi A",
      "Ripke S",
      "Lee JC",
      "Jostins L",
      "Shah T",
      "Abedian S",
      "Cheon JH",
      "Cho J",
      "Dayani NE",
      "Franke L",
      "Fuyuno Y",
      "Hart A",
      "Juyal RC",
      "Juyal G",
      "Kim WH",
      "Morris AP",
      "Poustchi H",
      "Newman WG",
      "Midha V",
      "Orchard TR",
      "Vahedi H",
      "Sood A",
      "Sung JY",
      "Malekzadeh R",
      "Westra HJ",
      "Yamazaki K",
      "Yang SK",
      "Barrett JC",
      "Alizadeh BZ",
      "Parkes M",
      "Bk T",
      "Daly MJ",
      "Kubo M",
      "Anderson CA",
      "Weersma RK"
    ],
    "journal": "Nature genetics",
    "year": 2015,
    "type": "Meta-analysis",
    "evidence": 5,
    "topics": [
      "ibd-biologics"
    ]
  },
  {
    "pmid": "26303131",
    "doi": "10.1038/ajg.2015.233",
    "pmc": null,
    "title": "Selecting Therapeutic Targets in Inflammatory Bowel Disease (STRIDE): Determining Therapeutic Goals for Treat-to-Target",
    "authors": [
      "Peyrin-Biroulet L",
      "Sandborn W",
      "Sands BE",
      "Reinisch W",
      "Bemelman W",
      "Bryant RV",
      "D'Haens G",
      "Dotan I",
      "Dubinsky M",
      "Feagan B",
      "Fiorino G",
      "Gearry R",
      "Krishnareddy S",
      "Lakatos PL",
      "Loftus EV Jr",
      "Marteau P",
      "Munkholm P",
      "Murdoch TB",
      "Ordás I",
      "Panaccione R",
      "Riddell RH",
      "Ruel J",
      "Rubin DT",
      "Samaan M",
      "Siegel CA",
      "Silverberg MS",
      "Stoker J",
      "Schreiber S",
      "Travis S",
      "Van Assche G",
      "Danese S",
      "Panes J",
      "Bouguen G",
      "O'Donnell S",
      "Pariente B",
      "Winer S",
      "Hanauer S",
      "Colombel JF"
    ],
    "journal": "The American journal of gastroenterology",
    "year": 2015,
    "type": "Systematic review",
    "evidence": 5,
    "topics": [
      "ibd-quality-of-life"
    ]
  },
  {
    "pmid": "40553742",
    "doi": "10.1053/j.gastro.2025.06.011",
    "pmc": null,
    "title": "Whole Food Diet Induces Remission in Children and Young Adults With Mild to Moderate Crohn's Disease and Is More Tolerable Than Exclusive Enteral Nutrition: A Randomized Controlled Trial",
    "authors": [
      "Aharoni-Frutkoff Y",
      "Plotkin L",
      "Pollak D",
      "Livovsky J",
      "Focht G",
      "Lev-Tzion R",
      "Ledder O",
      "Assa A",
      "Yogev D",
      "Orlanski-Meyer E",
      "Broide E",
      "Kierkuś J",
      "Kang B",
      "Weiss B",
      "Aloi M",
      "Schwerd T",
      "Shouval DS",
      "Bramuzzo M",
      "Griffiths AM",
      "Yassour M",
      "Turner D"
    ],
    "journal": "Gastroenterology",
    "year": 2025,
    "type": "Randomised controlled trial",
    "evidence": 4,
    "topics": [
      "ibd-diet"
    ]
  },
  {
    "pmid": "39853756",
    "doi": "10.1111/eci.14389",
    "pmc": null,
    "title": "The use of the Crohn's disease exclusion diet (CDED) in adults with Crohn's disease: A randomized controlled trial",
    "authors": [
      "Pasta A",
      "Formisano E",
      "Calabrese F",
      "Apollonio M",
      "Demarzo MG",
      "Marabotto E",
      "Furnari M",
      "Giannini EG",
      "Pisciotta L",
      "Bodini G"
    ],
    "journal": "European journal of clinical investigation",
    "year": 2025,
    "type": "Randomised controlled trial",
    "evidence": 4,
    "topics": [
      "ibd-trigger-foods"
    ]
  },
  {
    "pmid": "39581202",
    "doi": "10.1016/S0140-6736(24)01762-8",
    "pmc": null,
    "title": "Efficacy and safety of mirikizumab in patients with moderately-to-severely active Crohn's disease: a phase 3, multicentre, randomised, double-blind, placebo-controlled and active-controlled, treat-through study",
    "authors": [
      "Ferrante M",
      "D'Haens G",
      "Jairath V",
      "Danese S",
      "Chen M",
      "Ghosh S",
      "Hisamatsu T",
      "Kierkus J",
      "Siegmund B",
      "Bragg SM",
      "Crandall W",
      "Durand F",
      "Hon E",
      "Lin Z",
      "Lopes MU",
      "Morris N",
      "Protic M",
      "Carlier H",
      "Sands BE"
    ],
    "journal": "Lancet (London, England)",
    "year": 2024,
    "type": "Randomised controlled trial",
    "evidence": 4,
    "topics": [
      "ibd-epidemiology"
    ]
  },
  {
    "pmid": "34739863",
    "doi": "10.1016/S2468-1253(21)00299-5",
    "pmc": null,
    "title": "The Crohn's disease exclusion diet for induction and maintenance of remission in adults with mild-to-moderate Crohn's disease (CDED-AD): an open-label, pilot, randomised trial",
    "authors": [
      "Yanai H",
      "Levine A",
      "Hirsch A",
      "Boneh RS",
      "Kopylov U",
      "Eran HB",
      "Cohen NA",
      "Ron Y",
      "Goren I",
      "Leibovitzh H",
      "Wardi J",
      "Zittan E",
      "Ziv-Baran T",
      "Abramas L",
      "Fliss-Isakov N",
      "Raykhel B",
      "Gik TP",
      "Dotan I",
      "Maharshak N"
    ],
    "journal": "The lancet. Gastroenterology & hepatology",
    "year": 2022,
    "type": "Randomised controlled trial",
    "evidence": 4,
    "topics": [
      "ibd-diet",
      "ibd-trigger-foods"
    ]
  },
  {
    "pmid": "31586453",
    "doi": "10.1053/j.gastro.2019.09.024",
    "pmc": null,
    "title": "Effects of Low FODMAP Diet on Symptoms, Fecal Microbiome, and Markers of Inflammation in Patients With Quiescent Inflammatory Bowel Disease in a Randomized Trial",
    "authors": [
      "Cox SR",
      "Lindsay JO",
      "Fromentin S",
      "Stagg AJ",
      "McCarthy NE",
      "Galleron N",
      "Ibraim SB",
      "Roume H",
      "Levenez F",
      "Pons N",
      "Maziers N",
      "Lomer MC",
      "Ehrlich SD",
      "Irving PM",
      "Whelan K"
    ],
    "journal": "Gastroenterology",
    "year": 2020,
    "type": "Randomised controlled trial",
    "evidence": 4,
    "topics": [
      "ibd-diet",
      "ibd-quality-of-life"
    ]
  },
  {
    "pmid": "31170412",
    "doi": "10.1053/j.gastro.2019.04.021",
    "pmc": null,
    "title": "Crohn's Disease Exclusion Diet Plus Partial Enteral Nutrition Induces Sustained Remission in a Randomized Controlled Trial",
    "authors": [
      "Levine A",
      "Wine E",
      "Assa A",
      "Sigall Boneh R",
      "Shaoul R",
      "Kori M",
      "Cohen S",
      "Peleg S",
      "Shamaly H",
      "On A",
      "Millman P",
      "Abramas L",
      "Ziv-Baran T",
      "Grant S",
      "Abitbol G",
      "Dunn KA",
      "Bielawski JP",
      "Van Limbergen J"
    ],
    "journal": "Gastroenterology",
    "year": 2019,
    "type": "Randomised controlled trial",
    "evidence": 4,
    "topics": [
      "ibd-diet",
      "ibd-trigger-foods"
    ]
  },
  {
    "pmid": "31553834",
    "doi": "10.1056/NEJMoa1905725",
    "pmc": null,
    "title": "Vedolizumab versus Adalimumab for Moderate-to-Severe Ulcerative Colitis",
    "authors": [
      "Sands BE",
      "Peyrin-Biroulet L",
      "Loftus EV Jr",
      "Danese S",
      "Colombel JF",
      "Törüner M",
      "Jonaitis L",
      "Abhyankar B",
      "Chen J",
      "Rogers R",
      "Lirio RA",
      "Bornstein JD",
      "Schreiber S"
    ],
    "journal": "The New England journal of medicine",
    "year": 2019,
    "type": "Randomised controlled trial",
    "evidence": 4,
    "topics": [
      "ibd-epidemiology"
    ]
  },
  {
    "pmid": "7967919",
    "doi": "10.1016/s0025-7125(16)30110-9",
    "pmc": null,
    "title": "Nutrition support in inflammatory bowel disease",
    "authors": [
      "Lewis JD",
      "Fisher RL"
    ],
    "journal": "The Medical clinics of North America",
    "year": 1994,
    "type": "Randomised controlled trial",
    "evidence": 4,
    "topics": [
      "ibd-trigger-foods"
    ]
  },
  {
    "pmid": "41770539",
    "doi": "10.1001/jama.2026.0872",
    "pmc": null,
    "title": "Chronic, Noninfectious Diarrhea: A Review",
    "authors": [
      "Singh P",
      "Lee A",
      "Sheth NM",
      "Chey WD"
    ],
    "journal": "JAMA",
    "year": 2026,
    "type": "Review",
    "evidence": 3,
    "topics": [
      "ibd-diet"
    ]
  },
  {
    "pmid": "39475082",
    "doi": "10.1093/ecco-jcc/jjae082",
    "pmc": "PMC11522978",
    "title": "Epidemiology of Inflammatory Bowel Disease across the Ages in the Era of Advanced Therapies",
    "authors": [
      "Caron B",
      "Honap S",
      "Peyrin-Biroulet L"
    ],
    "journal": "Journal of Crohn's & colitis",
    "year": 2024,
    "type": "Review",
    "evidence": 3,
    "topics": [
      "ibd-epidemiology"
    ]
  },
  {
    "pmid": "39475081",
    "doi": "10.1093/ecco-jcc/jjae087",
    "pmc": "PMC11523044",
    "title": "Considerations in Paediatric and Adolescent Inflammatory Bowel Disease",
    "authors": [
      "Vuijk SA",
      "Camman AE",
      "de Ridder L"
    ],
    "journal": "Journal of Crohn's & colitis",
    "year": 2024,
    "type": "Review",
    "evidence": 3,
    "topics": [
      "ibd-trigger-foods"
    ]
  },
  {
    "pmid": "38505875",
    "doi": "10.1002/ncp.11146",
    "pmc": null,
    "title": "Dietary therapies for adult and pediatric inflammatory bowel disease",
    "authors": [
      "Deas J",
      "Shah ND",
      "Konijeti GG",
      "Lundin A",
      "Lanser O",
      "Magavi P",
      "Ali S"
    ],
    "journal": "Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition",
    "year": 2024,
    "type": "Review",
    "evidence": 3,
    "topics": [
      "ibd-trigger-foods"
    ]
  },
  {
    "pmid": "36753033",
    "doi": "10.1007/s11894-023-00863-y",
    "pmc": null,
    "title": "Mild Crohn's Disease: Definition and Management",
    "authors": [
      "Claytor J",
      "Kumar P",
      "Ananthakrishnan AN",
      "Colombel JF",
      "Agrawal M",
      "Ungaro RC"
    ],
    "journal": "Current gastroenterology reports",
    "year": 2023,
    "type": "Review",
    "evidence": 3,
    "topics": [
      "ibd-diet"
    ]
  },
  {
    "pmid": "34836263",
    "doi": "10.3390/nu13114008",
    "pmc": "PMC8624004",
    "title": "Iron Deficiency Anemia in Inflammatory Bowel Diseases-A Narrative Review",
    "authors": [
      "Mahadea D",
      "Adamczewska E",
      "Ratajczak AE",
      "Rychter AM",
      "Zawada A",
      "Eder P",
      "Dobrowolska A",
      "Krela-Kaźmierczak I"
    ],
    "journal": "Nutrients",
    "year": 2021,
    "type": "Review",
    "evidence": 3,
    "topics": [
      "ibd-quality-of-life"
    ]
  },
  {
    "pmid": "32460374",
    "doi": "10.1111/jdv.16677",
    "pmc": null,
    "title": "Hidradenitis suppurativa: an update on epidemiology, phenotypes, diagnosis, pathogenesis, comorbidities and quality of life",
    "authors": [
      "Nguyen TV",
      "Damiani G",
      "Orenstein LAV",
      "Hamzavi I",
      "Jemec GB"
    ],
    "journal": "Journal of the European Academy of Dermatology and Venereology : JEADV",
    "year": 2021,
    "type": "Review",
    "evidence": 3,
    "topics": [
      "ibd-quality-of-life"
    ]
  },
  {
    "pmid": "30772097",
    "doi": "10.1016/j.jaad.2018.11.058",
    "pmc": null,
    "title": "Joint AAD-NPF guidelines of care for the management and treatment of psoriasis with awareness and attention to comorbidities",
    "authors": [
      "Elmets CA",
      "Leonardi CL",
      "Davis DMR",
      "Gelfand JM",
      "Lichten J",
      "Mehta NN",
      "Armstrong AW",
      "Connor C",
      "Cordoro KM",
      "Elewski BE",
      "Gordon KB",
      "Gottlieb AB",
      "Kaplan DH",
      "Kavanaugh A",
      "Kivelevitch D",
      "Kiselica M",
      "Korman NJ",
      "Kroshinsky D",
      "Lebwohl M",
      "Lim HW",
      "Paller AS",
      "Parra SL",
      "Pathy AL",
      "Prater EF",
      "Rupani R",
      "Siegel M",
      "Stoff B",
      "Strober BE",
      "Wong EB",
      "Wu JJ",
      "Hariharan V",
      "Menter A"
    ],
    "journal": "Journal of the American Academy of Dermatology",
    "year": 2019,
    "type": "Review",
    "evidence": 3,
    "topics": [
      "ibd-quality-of-life"
    ]
  },
  {
    "pmid": "27830906",
    "doi": "10.4045/tidsskr.16.0134",
    "pmc": null,
    "title": "Fatigue in inflammatory bowel disease",
    "authors": [
      "Grimstad T",
      "Norheim KB"
    ],
    "journal": "Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke",
    "year": 2016,
    "type": "Review",
    "evidence": 3,
    "topics": [
      "ibd-quality-of-life"
    ]
  },
  {
    "pmid": "40307548",
    "doi": "10.1038/s41586-025-08940-0",
    "pmc": "PMC12158780",
    "title": "Global evolution of inflammatory bowel disease across epidemiologic stages",
    "authors": [
      "Hracs L",
      "Windsor JW",
      "Gorospe J",
      "Cummings M",
      "Coward S",
      "Buie MJ",
      "Quan J",
      "Goddard Q",
      "Caplan L",
      "Markovinović A",
      "Williamson T",
      "Abbey Y",
      "Abdullah M",
      "Abreu MT",
      "Ahuja V",
      "Raja Ali RA",
      "Altuwaijri M",
      "Balderramo D",
      "Banerjee R",
      "Benchimol EI",
      "Bernstein CN",
      "Brunet-Mas E",
      "Burisch J",
      "Chong VH",
      "Dotan I",
      "Dutta U",
      "El Ouali S",
      "Forbes A",
      "Forss A",
      "Gearry R",
      "Dao VH",
      "Hartono JL",
      "Hilmi I",
      "Hodges P",
      "Jones GR",
      "Juliao-Baños F",
      "Kaibullayeva J",
      "Kelly P",
      "Kobayashi T",
      "Kotze PG",
      "Lakatos PL",
      "Lees CW",
      "Limsrivilai J",
      "Lo B",
      "Loftus EV Jr",
      "Ludvigsson JF",
      "Mak JWY",
      "Miao Y",
      "Ng KK",
      "Okabayashi S",
      "Olén O",
      "Panaccione R",
      "Paudel MS",
      "Quaresma AB",
      "Rubin DT",
      "Simadibrata M",
      "Sun Y",
      "Suzuki H",
      "Toro M",
      "Turner D",
      "Iade B",
      "Wei SC",
      "Yamamoto-Furusho JK",
      "Yang SK",
      "Ng SC",
      "Kaplan GG"
    ],
    "journal": "Nature",
    "year": 2025,
    "type": "Journal article",
    "evidence": 2,
    "topics": [
      "ibd-epidemiology"
    ]
  },
  {
    "pmid": "38315582",
    "doi": "10.1002/ueg2.12532",
    "pmc": "PMC11017770",
    "title": "Psychological symptoms and quality of life in patients with inflammatory bowel disease in China: A multicenter study",
    "authors": [
      "Zhang J",
      "Liu C",
      "An P",
      "Chen M",
      "Wei Y",
      "Li J",
      "Zeng S",
      "Xiang D",
      "Cai Y",
      "Li J",
      "Chen B",
      "Cui L",
      "Qian J",
      "Liu Z",
      "Jiang C",
      "Shi J",
      "Wu K",
      "Dong W"
    ],
    "journal": "United European gastroenterology journal",
    "year": 2024,
    "type": "Journal article",
    "evidence": 2,
    "topics": [
      "ibd-quality-of-life"
    ]
  }
]