IBD Evidence

Evidence map

Inflammatory bowel disease quality of life: what the evidence base looks like

16 publications, 3 of them trials and 8 syntheses. This page describes the shape of that literature rather than summarising its conclusions.

Updated 4 min read 16 citations

Ground-floor pharmacy premises on Teltower Damm in Berlin-Zehlendorf, Germany
Singlespeedfahrer · CC0 · Wikimedia Commons
What the evidence on inflammatory bowel disease quality of life is made of Of 16 publications on this topic, the breakdown by study type: 8 meta-analysis, 3 randomised trial, 4 review, 1 other. 8341meta-analysis (8)randomised trial (3)review (4)other (1)
16 publications, by study type. Volume is not strength — the same count can be a settled question or a pile of commentary, and which one it is depends almost entirely on this breakdown. Harvested from PubMed and Crossref; publication type as recorded by the source.

What this literature is made of

The synthesis is ahead of the primary literature here — reviews and meta-analyses drawing on a modest number of underlying studies. Treat confident conclusions with the caution the sample size deserves.

The distinction that matters most is between synthesis and primary research. A meta-analysis pools trials and is the closest thing to a settled answer a field produces. A narrative review is one group's reading of the same material and can be selective without being dishonest. Counting them together, which most citation counts do, obscures exactly the thing you want to know.

When the inflammatory bowel disease quality of life literature was published Publication years for the 16 papers on this topic, grouped into bands from before 2015 through to 2023 onwards. 2020-20227 papers2023 onwards5 papers2015-20194 papers
Still active. The most recent paper here is from 2024, so this is a field where an answer written today may not hold for long. Publication years as recorded by PubMed and Crossref.

How this page is built

Everything above is computed from the citations this site harvested from PubMed and Crossref, not written by hand. When the weekly harvest finds a new paper on this topic, these counts change and the characterisation changes with them. That is the point: a hand-written claim about how strong an evidence base is starts decaying the day it is written.

Publication type is taken as the source records it. That is imperfect — journals label inconsistently, and a paper indexed as a "review" may be a systematic one — so treat the bands as approximate. They are accurate enough to distinguish a trial literature from a commentary literature, which is the distinction that matters.

Labelled chemical bottles standing together on a laboratory bench
564dude · CC BY-SA 3.0 · Wikimedia Commons

The strongest work on this topic

Ordered by study design first, then recency. The full set is listed in the references below.

  1. Risk factors for herpes zoster infections: a systematic review and meta-analysis unveiling common trends and heterogeneity patterns — Steinmann M, Lampe D, Grosser J et al., 2024, meta-analysis
  2. Nutrition, Nutritional Status, Micronutrients Deficiency, and Disease Course of Inflammatory Bowel Disease — Valvano M, Capannolo A, Cesaro N et al., 2023, systematic review
  3. STRIDE-II: An Update on the Selecting Therapeutic Targets in Inflammatory Bowel Disease (STRIDE) Initiative of the International Organization for the Study of IBD (IOIBD): Determining Therapeutic Goals for Treat-to-Target strategies in IBD — Turner D, Ricciuto A, Lewis A et al., 2021, systematic review
  4. ACG Clinical Guideline: Management of Irritable Bowel Syndrome — Lacy BE, Pimentel M, Brenner DM et al., 2021, clinical guideline
  5. Prevalence of symptoms of anxiety and depression in patients with inflammatory bowel disease: a systematic review and meta-analysis00014-5) — Barberio B, Zamani M, Black CJ et al., 2021, meta-analysis
  6. Pediatric Psoriasis Comorbidities — Kittler NW, Cordoro KM, 2020, clinical guideline
  7. Quality of Life in Inflammatory Bowel Disease: A Systematic Review and Meta-analyses-Part I — Knowles SR, Graff LA, Wilding H et al., 2018, meta-analysis
  8. Selecting Therapeutic Targets in Inflammatory Bowel Disease (STRIDE): Determining Therapeutic Goals for Treat-to-Target — Peyrin-Biroulet L, Sandborn W, Sands BE et al., 2015, systematic review
  9. Early and Sustained Symptom Control with Mirikizumab in Patients with Ulcerative Colitis in the Phase 3 LUCENT Programme — Danese S, Dignass A, Matsuoka K et al., 2024, randomised controlled trial
  10. Acceptance and Commitment Therapy for Adults Living With Inflammatory Bowel Disease and Distress: A Randomized Controlled Trial — Naude C, Skvarc D, Maunick B et al., 2024, randomised controlled trial
How much research is there on inflammatory bowel disease quality of life?
16 publications are indexed here, of which 3 are trials and 8 are syntheses.
Does more research mean a stronger conclusion?
No. Composition matters more than volume — five randomised trials support a claim far better than fifty commentaries, and citation counts do not distinguish between them.
How current is this?
The most recent paper indexed here is from 2024. The set is refreshed weekly from PubMed and Crossref.
Why does this page not tell me the answer?
Because summarising a literature into a conclusion requires reading it, and doing that automatically is how confident nonsense gets published. This page tells you how much weight a conclusion could bear; the articles on this site do the interpreting.

References

Every citation below links to the original peer-reviewed record on PubMed or via DOI. Nothing here is a substitute for medical advice.

  1. Risk factors for herpes zoster infections: a systematic review and meta-analysis unveiling common trends and heterogeneity patterns Steinmann M, Lampe D, Grosser J, et al. · Infection · 2024 · Meta-analysis DOIPubMed 38236326Full text
  2. Nutrition, Nutritional Status, Micronutrients Deficiency, and Disease Course of Inflammatory Bowel Disease Valvano M, Capannolo A, Cesaro N, et al. · Nutrients · 2023 · Systematic review DOIPubMed 37686856Full text
  3. Prevalence of symptoms of anxiety and depression in patients with inflammatory bowel disease: a systematic review and meta-analysis Barberio B, Zamani M, Black CJ, et al. · The lancet. Gastroenterology & hepatology · 2021 · Meta-analysis DOIPubMed 33721557
  4. STRIDE-II: An Update on the Selecting Therapeutic Targets in Inflammatory Bowel Disease (STRIDE) Initiative of the International Organization for the Study of IBD (IOIBD): Determining Therapeutic Goals for Treat-to-Target strategies in IBD Turner D, Ricciuto A, Lewis A, et al. · Gastroenterology · 2021 · Systematic review DOIPubMed 33359090
  5. ACG Clinical Guideline: Management of Irritable Bowel Syndrome Lacy BE, Pimentel M, Brenner DM, et al. · The American journal of gastroenterology · 2021 · Clinical guideline DOIPubMed 33315591
  6. Pediatric Psoriasis Comorbidities Kittler NW, Cordoro KM · Skin therapy letter · 2020 · Clinical guideline PubMed 33196156
  7. Quality of Life in Inflammatory Bowel Disease: A Systematic Review and Meta-analyses-Part I Knowles SR, Graff LA, Wilding H, et al. · Inflammatory bowel diseases · 2018 · Meta-analysis DOIPubMed 29562277
  8. Selecting Therapeutic Targets in Inflammatory Bowel Disease (STRIDE): Determining Therapeutic Goals for Treat-to-Target Peyrin-Biroulet L, Sandborn W, Sands BE, et al. · The American journal of gastroenterology · 2015 · Systematic review DOIPubMed 26303131
  9. Early and Sustained Symptom Control with Mirikizumab in Patients with Ulcerative Colitis in the Phase 3 LUCENT Programme Danese S, Dignass A, Matsuoka K, et al. · Journal of Crohn's & colitis · 2024 · Randomised controlled trial DOIPubMed 38869019Full text
  10. Acceptance and Commitment Therapy for Adults Living With Inflammatory Bowel Disease and Distress: A Randomized Controlled Trial Naude C, Skvarc D, Maunick B, et al. · The American journal of gastroenterology · 2024 · Randomised controlled trial DOIPubMed 39162706Full text
  11. Effects of Low FODMAP Diet on Symptoms, Fecal Microbiome, and Markers of Inflammation in Patients With Quiescent Inflammatory Bowel Disease in a Randomized Trial Cox SR, Lindsay JO, Fromentin S, et al. · Gastroenterology · 2020 · Randomised controlled trial DOIPubMed 31586453
  12. Hidradenitis suppurativa: an update on epidemiology, phenotypes, diagnosis, pathogenesis, comorbidities and quality of life Nguyen TV, Damiani G, Orenstein LAV, et al. · Journal of the European Academy of Dermatology and Venereology : JEADV · 2021 · Review DOIPubMed 32460374
  13. Iron Deficiency Anemia in Inflammatory Bowel Diseases-A Narrative Review Mahadea D, Adamczewska E, Ratajczak AE, et al. · Nutrients · 2021 · Review DOIPubMed 34836263Full text
  14. Joint AAD-NPF guidelines of care for the management and treatment of psoriasis with awareness and attention to comorbidities Elmets CA, Leonardi CL, Davis DMR, et al. · Journal of the American Academy of Dermatology · 2019 · Review DOIPubMed 30772097
  15. Fatigue in inflammatory bowel disease Grimstad T, Norheim KB · Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke · 2016 · Review DOIPubMed 27830906
  16. Psychological symptoms and quality of life in patients with inflammatory bowel disease in China: A multicenter study Zhang J, Liu C, An P, et al. · United European gastroenterology journal · 2024 · Journal article DOIPubMed 38315582Full text